Will & Grace are best friends. Will is a gay lawyer and Grace is a straight interior designer. They both live in New York. Grace is engaged to a real jerk, but when that relationship falls apart, she moves in with Will. This is only supposed to be until Grace finds a place of her own, but she and Will end up with each other as permanent roommates. Also in the cast are Jack, Will's flamboyant gay friend and Karen, Graces' secretary/assistant who doesn't really need to work because she married money several times.。拳击大赛决赛在即,晓峰为当职业拳手赢得奖金而专心训练备战;女团选拔即将开始,一心走上演艺之路的莎莎却因为父亲的反对决定离家出走。不料在学校里本就是斗气冤家的两人,偏偏遭遇了爱管闲事的变身狂人,将两人的身体互换!直男变少女,少女变拳手,本就火星撞地球的两人被迫介入对方的生活,还得扮情侣、假同居、见家长、斗情敌,经历了笑料不断的各种闹剧后,两人能否如愿换回自己的身体,实现各自的梦想呢?身份的错位是否带给他们新的人生体验呢?两人的关系又将向何发展呢?。